| NCAAF | 11/18 22:00 | 1 | North Dakota State v Northern Iowa Panthers | L | 48-27 | |
| NCAAF | 11/11 20:00 | 1 | Northern Iowa Panthers v Missouri State | L | 16-35 | |
| NCAAF | 11/04 18:00 | 1 | Western Illinois v Northern Iowa Panthers | W | 6-50 | |
| NCAAF | 10/28 17:00 | 1 | Northern Iowa Panthers v Illinois State | W | 24-21 | |
| NCAAF | 10/21 21:00 | 1 | North Dakota v Northern Iowa Panthers | W | 0-27 | |
| NCAAF | 10/14 19:00 | 1 | Northern Iowa Panthers v South Dakota State | L | 6-41 | |
| NCAAF | 10/07 23:00 | 1 | Northern Iowa Panthers v Indiana State | W | 27-20 | |
| NCAAF | 09/30 18:00 | 1 | [30] Youngstown State v Northern Iowa Panthers [77] | W | 41-44 | |
| NCAAF | 09/16 22:00 | 1 | Northern Iowa Panthers v Idaho State | W | 41-17 | |
| NCAAF | 09/09 21:00 | 1 | Weber State v Northern Iowa Panthers | L | 34-17 | |
| NCAAF | 09/02 18:00 | 1 |
[18] Northern Iowa Panthers
v
Iowa State
[24] 
|
L | 9-30 | |
| NCAAF | 11/19 19:00 | 1 | Northern Iowa Panthers v South Dakota | W | 58-14 | |
| NCAAF | 11/05 21:00 | 1 | South Dakota State v Northern Iowa Panthers | L | 31-28 | |
| NCAAF | 10/29 19:00 | 1 | Northern Iowa Panthers v Southern Illinois Salukis | W | 37-36 | |
| NCAAF | 10/22 21:00 | 1 | Missouri State v Northern Iowa Panthers | W | 20-41 | |
| NCAAF | 10/15 21:00 | 1 | [100] Utah Tech v Northern Iowa Panthers [80] | W | 14-41 | |
| NCAAF | 10/08 21:00 | 1 | [62] Illinois State v Northern Iowa Panthers [72] | L | 23-21 | |
| NCAAF | 10/01 21:00 | 1 | [84] Indiana State v Northern Iowa Panthers [90] | W | 14-20 | |
| NCAAF | 09/24 20:00 | 1 | Northern Iowa Panthers v Western Illinois | W | 52-17 | |
| NCAAF | 09/17 21:00 | 1 | Sacramento State v Northern Iowa Panthers | L | 37-21 | |
| NCAAF | 09/10 20:00 | 1 | Northern Iowa Panthers v North Dakota | L | 27-29 | |
| NCAAF | 09/03 17:00 | 1 |
[12] Northern Iowa Panthers
v
Air Force
[63] 
|
L | 17-48 | |
| NCAAF | 11/27 21:00 | 1 | Northern Iowa Panthers v Eastern Washington | L | 9-19 | |
| NCAAF | 11/20 19:00 | 1 | Western Illinois v Northern Iowa Panthers | W | 3-41 | |
| NCAAF | 11/13 20:00 | 1 | Northern Iowa Panthers v Missouri State | L | 27-34 | |
| NCAAF | 11/06 17:00 | 1 | [45] Northern Iowa Panthers v Illinois State [84] | L | 10-17 | |
| NCAAF | 10/30 21:00 | 1 | [12] Southern Illinois Salukis v Northern Iowa Panthers [56] | W | 16-23 | |
| NCAAF | 10/23 19:00 | 1 | [69] Northern Iowa Panthers v South Dakota State [13] | W | 26-17 | |
| NCAAF | 10/16 21:00 | 1 | South Dakota v Northern Iowa Panthers | L | 34-21 | |
| NCAAF | 10/09 18:00 | 1 | Northern Iowa Panthers v North Dakota State | L | 20-34 |