Home History
| NCAAF | 2000/11/11 12:00 | Michigan v Penn State | L | 33-11 |
| NCAAF | 2000/11/04 12:00 | Penn State v Iowa | L | 23-26 |
| NCAAF | 2000/10/28 12:00 | Indiana v Penn State | W | 24-27 |
| NCAAF | 2000/10/21 12:00 | Penn State v Illinois | W | 39-25 |
| NCAAF | 2000/10/07 12:00 | Minnesota v Penn State | L | 25-16 |
| NCAAF | 2000/09/30 12:00 | Penn State v Purdue | W | 22-20 |
| NCAAF | 2000/09/23 12:00 | Ohio State v Penn State | L | 45-6 |
| NCAAF | 2000/09/16 12:00 | Pittsburgh v Penn State | L | 12-0 |
Away History
| NCAAF | 2000/11/11 12:00 | Michigan State v Purdue | W | 30-10 |
| NCAAF | 2000/11/04 12:00 | Ohio State v Michigan State | L | 27-13 |
| NCAAF | 2000/10/28 12:00 | Michigan State v Illinois | W | 14-10 |
| NCAAF | 2000/10/21 12:00 | Michigan v Michigan State | L | 14-0 |
| NCAAF | 2000/10/14 12:00 | Michigan State v Wisconsin | L | 10-17 |
| NCAAF | 2000/10/07 12:00 | Iowa v Michigan State | L | 21-16 |
| NCAAF | 2000/09/30 12:00 | Michigan State v Northwestern | L | 17-37 |
| NCAAF | 2000/09/23 12:00 | Michigan State v Notre Dame | W | 27-21 |