Head to Head
| NCAAF | 2009/11/21 12:00 | Michigan State v Penn State | W | 14-42 |
| NCAAF | 2008/11/22 12:00 | Penn State v Michigan State | W | 49-18 |
| NCAAF | 2007/11/17 12:00 | Michigan State v Penn State | L | 35-31 |
| NCAAF | 2006/11/18 12:00 | Penn State v Michigan State | W | 17-13 |
| NCAAF | 2005/11/19 12:00 | Michigan State v Penn State | W | 22-31 |
| NCAAF | 2004/11/20 12:00 | Penn State v Michigan State | W | 37-13 |
| NCAAF | 2003/11/22 12:00 | Michigan State v Penn State | L | 41-10 |
| NCAAF | 2002/11/23 12:00 | Penn State v Michigan State | W | 61-7 |
Home History
| NCAAF | 2010/11/20 12:00 | Indiana v Penn State | W | 24-41 |
| NCAAF | 2010/11/13 12:00 | Ohio State v Penn State | L | 38-14 |
| NCAAF | 2010/11/06 12:00 | Penn State v Northwestern | W | 35-21 |
| NCAAF | 2010/10/30 12:00 | Penn State v Michigan | W | 41-31 |
| NCAAF | 2010/10/23 12:00 | Minnesota v Penn State | W | 21-33 |
| NCAAF | 2010/10/09 12:00 | Penn State v Illinois | L | 13-33 |
| NCAAF | 2010/10/02 12:00 | Iowa v Penn State | L | 24-3 |
| NCAAF | 2010/09/25 12:00 | Penn State v Temple | W | 22-13 |
Away History
| NCAAF | 2010/11/20 12:00 | Michigan State v Purdue | W | 35-31 |
| NCAAF | 2010/11/06 12:00 | Michigan State v Minnesota | W | 31-8 |
| NCAAF | 2010/10/30 12:00 | Iowa v Michigan State | L | 37-6 |
| NCAAF | 2010/10/23 12:00 | Northwestern v Michigan State | W | 27-35 |
| NCAAF | 2010/10/16 12:00 | Michigan State v Illinois | W | 26-6 |
| NCAAF | 2010/10/09 12:00 | Michigan v Michigan State | W | 17-34 |
| NCAAF | 2010/10/02 12:00 | Michigan State v Wisconsin | W | 34-24 |
| NCAAF | 2010/09/25 12:00 | Michigan State v Northern Colorado | W | 45-7 |