[9] Mazatlán F.C. 0-1 Club América [2] 2021-03-20 03:00
Estadio: Estadio de Mazatlán Round: 12
Árbitro: Diego Montano Robles Home Manager: Francisco Palencia Away Manager: Santiago Solari
Head to Head
| México - Liga MX | 2020/09/03 01:00 | Club América v Mazatlán F.C. | L | 3-1 |
| Europa - Amistosos | 2018/07/08 23:30 | Mazatlán F.C. v Club América | L | 1-2 |
| México - Liga MX | 2016/08/14 02:00 | Club América v Mazatlán F.C. | D | 1-1 |
| México - Liga MX | 2016/03/05 23:00 | Club América v Mazatlán F.C. | L | 4-1 |
| México - Liga MX | 2015/09/20 01:30 | Mazatlán F.C. v Club América | L | 0-3 |
| México - Liga MX | 2015/02/07 01:30 | Mazatlán F.C. v Club América | D | 2-2 |
| México - Liga MX | 2014/08/16 22:00 | Club América v Mazatlán F.C. | L | 3-2 |
Home History
| México - Liga MX | 2021/03/14 01:00 | Tigres UANL v Mazatlán F.C. | W | 1-2 |
| México - Liga MX | 2021/03/07 03:00 | Mazatlán F.C. v Chivas de Guadalajara | D | 1-1 |
| México - Liga MX | 2021/03/04 03:00 | Cruz Azul v Mazatlán F.C. | L | 1-0 |
| México - Liga MX | 2021/02/27 03:30 | Mazatlán F.C. v Querétaro | W | 3-0 |
| México - Liga MX | 2021/02/20 03:30 | Juárez FC v Mazatlán F.C. | L | 1-0 |
| México - Liga MX | 2021/02/13 03:30 | Mazatlán F.C. v Atlético San Luis | L | 0-3 |
| México - Liga MX | 2021/02/07 18:00 | Toluca v Mazatlán F.C. | L | 4-1 |
| México - Liga MX | 2021/01/30 03:30 | Mazatlán F.C. v Pachuca | W | 1-0 |
Away History
| México - Liga MX | 2021/03/15 02:00 | Chivas de Guadalajara v Club América | W | 0-3 |
| México - Liga MX | 2021/03/07 01:00 | Club América v León | W | 2-1 |
| México - Liga MX | 2021/03/04 03:06 | Tijuana v Club América | W | 0-2 |
| México - Liga MX | 2021/02/28 01:00 | Club América v Pachuca | W | 2-0 |
| México - Liga MX | 2021/02/14 03:00 | Club América v Querétaro | W | 2-1 |
| México - Liga MX | 2021/02/07 01:00 | Club América v Puebla | W | 1-0 |
| México - Liga MX | 2021/02/01 01:06 | Santos Laguna v Club América | D | 1-1 |
| México - Liga MX | 2021/01/27 02:30 | Club América v Juárez FC | W | 2-0 |