[2] Club América 2-0 Pumas de la UNAM [17] 2021-10-03 22:00
Estadio: Estadio Azteca Round: 12
Árbitro: Jorge Perez Home Manager: Santiago Solari Away Manager: Andrés Lillini
Head to Head
| México - Liga MX | 2021/05/03 02:05 | Pumas de la UNAM v Club América | W | 0-1 |
| México - Liga MX | 2020/10/04 02:00 | Club América v Pumas de la UNAM | D | 2-2 |
| Europa - Partidos amistosos | 2020/07/08 02:00 | Pumas de la UNAM v Club América | D | 0-0 |
| México - Liga MX | 2020/03/07 02:00 | Pumas de la UNAM v Club América | D | 3-3 |
| México - Liga MX | 2019/09/15 02:06 | Club América v Pumas de la UNAM | D | 1-1 |
| Clubes del Mundo - Amistosos | 2019/07/10 01:00 | Club América v Pumas de la UNAM | L | 0-3 |
| México - Liga MX | 2019/02/17 18:00 | Pumas de la UNAM v Club América | L | 1-0 |
| México - Liga MX | 2018/12/10 00:45 | Club América v Pumas de la UNAM | W | 6-1 |
Home History
| México - Liga MX | 2021/09/29 02:05 | Pachuca v Club América | D | 1-1 |
| México - Liga MX | 2021/09/26 02:00 | Club América v Chivas de Guadalajara | D | 0-0 |
| México - Liga MX | 2021/09/19 00:00 | Toluca v Club América | L | 3-1 |
| CONCACAF - Copa de Campeones | 2021/09/16 01:00 | Philadelphia Union v Club América | W | 0-2 |
| México - Liga MX | 2021/09/12 02:00 | Club América v Mazatlán F.C. | W | 2-0 |
| México - Liga MX | 2021/08/29 02:00 | León v Club América | D | 1-1 |
| México - Liga MX | 2021/08/22 22:00 | Club América v Tijuana | W | 2-0 |
| México - Liga MX | 2021/08/19 02:00 | Juárez FC v Club América | W | 1-2 |
Away History
| México - Liga MX | 2021/09/26 00:00 | Tigres UANL v Pumas de la UNAM | D | 0-0 |
| México - Liga MX | 2021/09/19 02:00 | Mazatlán F.C. v Pumas de la UNAM | D | 2-2 |
| Leagues Cup | 2021/09/16 03:00 | León v Pumas de la UNAM | L | 2-0 |
| México - Liga MX | 2021/09/12 22:00 | Pumas de la UNAM v Chivas de Guadalajara | D | 0-0 |
| México - Liga MX | 2021/08/29 17:00 | Toluca v Pumas de la UNAM | L | 2-1 |
| México - Liga MX | 2021/08/22 17:00 | Pumas de la UNAM v Puebla | W | 2-0 |
| México - Liga MX | 2021/08/18 02:00 | Necaxa v Pumas de la UNAM | L | 3-0 |
| México - Liga MX | 2021/08/14 22:00 | Pumas de la UNAM v Querétaro | D | 0-0 |