Estadio: Seibert Stadium Round: 1
Home Manager: Chris Hatcher Away Manager: Rusty Wright
| NCAAF | 2019/11/09 20:00 | Tennessee Chattanooga v Samford Bulldogs | W | 35-27 |
| NCAAF | 2018/09/22 23:00 | Samford Bulldogs v Tennessee Chattanooga | W | 20-27 |
| NCAAF | 2017/10/28 19:00 | Samford Bulldogs v Tennessee Chattanooga | W | 21-23 |
| NCAAF | 2021/10/16 17:30 | East Tennessee State v Tennessee Chattanooga | W | 16-21 |
| NCAAF | 2021/10/09 17:30 | Tennessee Chattanooga v VMI | L | 34-37 |
| NCAAF | 2021/10/02 17:30 | Western Carolina v Tennessee Chattanooga | W | 17-45 |
| NCAAF | 2021/09/18 16:00 | Tennessee Chattanooga v Kentucky | L | 23-28 |
| NCAAF | 2021/09/11 23:00 | Tennessee Chattanooga v North Alabama Lions | W | 20-0 |
| NCAAF | 2021/09/02 23:30 | Austin Peay v Tennessee Chattanooga | L | 30-20 |
| NCAAF | 2021/03/27 16:00 | Mercer v Tennessee Chattanooga | L | 35-28 |
| NCAAF | 2021/03/20 16:00 | Tennessee Chattanooga v Furman | W | 20-18 |
| NCAAF | 2021/10/16 17:30 | Samford Bulldogs v Wofford | W | 27-24 |
| NCAAF | 2021/10/02 22:00 | Samford Bulldogs v Mercer | L | 42-45 |
| NCAAF | 2021/09/25 19:00 | East Tennessee State v Samford Bulldogs | L | 55-48 |
| NCAAF | 2021/09/18 18:30 | Samford Bulldogs v Western Carolina | W | 42-37 |
| NCAAF | 2021/09/11 23:00 | Samford Bulldogs v Tennessee Martin | L | 27-33 |
| NCAAF | 2021/09/02 23:00 | Tennessee Tech v Samford Bulldogs | W | 14-52 |
| NCAAF | 2021/04/17 17:00 | Mercer v Samford Bulldogs | W | 20-44 |
| NCAAF | 2021/03/27 17:00 | Samford Bulldogs v The Citadel | W | 55-7 |