[14] Puebla 1-1 Club América [3] 2022-01-08 03:00
Estadio: Estadio Cuauhtémoc Round: 1
Árbitro: Oscar Mejia Garcia Home Manager: Nicolas Larcamon Away Manager: Santiago Solari
Head to Head
| México - Liga MX | 2021/08/08 00:00 | Club América v Puebla | L | 2-0 |
| México - Liga MX | 2021/02/07 01:00 | Club América v Puebla | L | 1-0 |
| México - Liga MX | 2020/09/09 02:00 | Puebla v Club América | L | 2-3 |
| México - Liga MX | 2020/02/05 02:30 | Puebla v Club América | L | 0-1 |
| México - Liga MX | 2019/10/27 00:00 | Club América v Puebla | L | 2-0 |
| México - Liga MX | 2019/03/10 01:00 | Club América v Puebla | L | 1-0 |
| México - Liga MX | 2018/09/22 02:00 | Puebla v Club América | L | 2-3 |
| México - Liga MX | 2018/04/21 00:00 | Puebla v Club América | W | 3-1 |
Home History
| México - Liga MX | 2021/11/29 02:05 | León v Puebla | L | 2-0 |
| México - Liga MX | 2021/11/26 01:00 | Puebla v León | W | 2-1 |
| México - Liga MX | 2021/11/21 03:00 | Puebla v Chivas de Guadalajara | W | 8-7 |
| México - Liga MX | 2021/11/06 01:00 | Puebla v Toluca | W | 1-0 |
| México - Liga MX | 2021/10/30 02:00 | Juárez FC v Puebla | W | 0-2 |
| México - Liga MX | 2021/10/23 22:00 | Puebla v León | L | 0-1 |
| México - Liga MX | 2021/10/20 00:00 | Puebla v Mazatlán F.C. | W | 2-0 |
| México - Liga MX | 2021/10/16 00:00 | Necaxa v Puebla | W | 0-1 |
Away History
| México - Liga MX | 2021/11/28 01:00 | Club América v Pumas de la UNAM | L | 1-3 |
| México - Liga MX | 2021/11/25 01:00 | Pumas de la UNAM v Club América | D | 0-0 |
| México - Liga MX | 2021/11/07 01:00 | Club América v Monterrey | D | 0-0 |
| México - Liga MX | 2021/10/31 23:05 | Cruz Azul v Club América | L | 2-1 |
| CONCACAF - Copa de Campeones | 2021/10/29 02:00 | Monterrey v Club América | L | 1-0 |
| México - Liga MX | 2021/10/24 00:00 | Club América v Tigres UANL | W | 1-0 |
| México - Liga MX | 2021/10/20 00:05 | Club América v Santos Laguna | W | 2-1 |
| México - Liga MX | 2021/10/17 00:00 | Atlético San Luis v Club América | W | 0-1 |