Estadio: Kirby Sports Center
Home Manager: Fran O'Hanlon Away Manager: Brett Nelson
| NCAAB | 2022/01/08 00:00 | Lafayette v Holy Cross | W | 74-79 |
| NCAAB | 2020/02/15 19:05 | Lafayette v Holy Cross | L | 72-62 |
| NCAAB | 2020/01/09 00:00 | Holy Cross v Lafayette | L | 64-82 |
| NCAAB | 2019/03/06 00:00 | Holy Cross v Lafayette | W | 79-74 |
| NCAAB | 2019/02/10 17:00 | Holy Cross v Lafayette | L | 67-69 |
| NCAAB | 2019/01/12 20:05 | Lafayette v Holy Cross | W | 70-77 |
| NCAAB | 2018/01/27 19:05 | Holy Cross v Lafayette | W | 85-74 |
| NCAAB | 2018/01/03 00:00 | Lafayette v Holy Cross | L | 60-48 |
| NCAAB | 2022/02/19 17:00 | Holy Cross v Navy | W | 55-50 |
| NCAAB | 2022/02/17 00:00 | Boston U v Holy Cross | L | 78-65 |
| NCAAB | 2022/02/15 00:00 | Estadounidense v Holy Cross | L | 60-54 |
| NCAAB | 2022/02/12 19:00 | Holy Cross v Bucknell | W | 78-72 |
| NCAAB | 2022/02/10 00:00 | Loyola Maryland v Holy Cross | W | 64-68 |
| NCAAB | 2022/02/07 23:00 | Holy Cross v Colgate | L | 60-87 |
| NCAAB | 2022/02/05 18:00 | Holy Cross v Army | W | 69-65 |
| NCAAB | 2022/02/01 00:00 | Holy Cross v Boston U | W | 75-70 |
| NCAAB | 2022/02/19 21:00 | Lafayette v Bucknell | L | 89-92 |
| NCAAB | 2022/02/17 00:00 | Loyola Maryland v Lafayette | W | 68-77 |
| NCAAB | 2022/02/14 23:00 | Lafayette v Colgate | L | 61-69 |
| NCAAB | 2022/02/12 17:00 | Lafayette v Lehigh | W | 73-69 |
| NCAAB | 2022/02/08 00:00 | Lafayette v Navy | L | 44-68 |
| NCAAB | 2022/02/05 19:00 | Bucknell v Lafayette | W | 72-74 |
| NCAAB | 2022/02/03 00:00 | Estadounidense v Lafayette | W | 62-71 |
| NCAAB | 2022/01/31 23:00 | Colgate v Lafayette | L | 72-61 |