Estadio: Bridgeforth Stadium and Zane Showker Field Round: 1
Home Manager: Curt Cignetti Away Manager: Dawson Odums
| NCAAF | 2022/09/03 19:30 | Norfolk State Spartans v Marshall | L | 3-55 |
| NCAAF | 2021/11/20 19:00 | South Carolina State Bulldogs v Norfolk State Spartans | L | 31-21 |
| NCAAF | 2021/11/13 18:00 | Norfolk State Spartans v Delaware State | L | 26-28 |
| NCAAF | 2021/11/06 18:00 | Norfolk State Spartans v North Carolina Central Eagles | L | 36-38 |
| NCAAF | 2021/10/30 18:00 | Morgan State Bears v Norfolk State Spartans | W | 20-31 |
| NCAAF | 2021/10/23 17:00 | Norfolk State Spartans v Howard | W | 45-31 |
| NCAAF | 2021/10/16 18:00 | Norfolk State Spartans v Lynchburg Dragons | W | 42-14 |
| NCAAF | 2021/10/02 18:00 | Norfolk State Spartans v Hampton | W | 47-44 |
| NCAAF | 2022/09/03 22:00 | Middle Tennessee St. v James Madison | W | 7-44 |
| NCAAF | 2021/12/18 02:15 | James Madison v North Dakota State | L | 14-20 |
| NCAAF | 2021/12/11 00:00 | Montana v James Madison | W | 6-28 |
| NCAAF | 2021/12/04 19:00 | SE Louisiana Lions v James Madison | W | 20-59 |
| NCAAF | 2021/11/20 19:00 | Towson v James Madison | W | 10-56 |
| NCAAF | 2021/11/13 20:30 | James Madison v William & Mary | W | 32-22 |
| NCAAF | 2021/11/06 19:30 | Campbell v James Madison | W | 14-51 |
| NCAAF | 2021/10/30 18:00 | Elon v James Madison | W | 21-45 |