| Uruguay - Liga B | 2022/06/14 18:00 | Rentistas - B v Defensor Sporting - B | L | 3-1 |
| Uruguay - Liga B | 2022/12/05 13:00 | Deportivo Maldonado - B v Defensor Sporting - B | L | 2-1 |
| Uruguay - Liga B | 2022/12/01 19:00 | Defensor Sporting - B v Danubio - B | L | 0-5 |
| Uruguay - Liga B | 2022/11/24 19:00 | Cerrito - B v Defensor Sporting - B | W | 0-1 |
| Uruguay - Liga B | 2022/11/21 19:00 | Club Nacional de Football - B v Defensor Sporting - B | L | 3-1 |
| Uruguay - Liga B | 2022/11/14 12:30 | Defensor Sporting - B v Albion FC - B | W | 5-1 |
| Uruguay - Liga B | 2022/11/04 13:00 | Centro Atlético Fénix - B v Defensor Sporting - B | L | 5-0 |
| Uruguay - Liga B | 2022/10/25 18:00 | Defensor Sporting - B v Cerro Largo - B | W | 4-0 |
| Uruguay - Liga B | 2022/10/11 13:00 | Atlético River Plate - B v Defensor Sporting - B | D | 0-0 |
| Uruguay - Liga B | 2022/12/05 19:00 | Rentistas - B v Centro Atlético Fénix - B | W | 1-0 |
| Uruguay - Liga B | 2022/11/21 19:00 | Rentistas - B v Atlético River Plate - B | D | 2-2 |
| Uruguay - Liga B | 2022/11/14 19:00 | Boston River - B v Rentistas - B | D | 3-3 |
| Uruguay - Liga B | 2022/11/10 19:00 | Rentistas - B v Liverpool FC (Montevideo) - B | D | 2-2 |
| Uruguay - Liga B | 2022/11/08 13:00 | Rentistas - B v Plaza Colonia - B | D | 1-1 |
| Uruguay - Liga B | 2022/11/03 18:00 | Montevideo Wanderers - B v Rentistas - B | L | 5-0 |
| Uruguay - Liga B | 2022/10/25 18:00 | Rentistas - B v Torque - B | L | 1-2 |
| Uruguay - Liga B | 2022/10/17 18:00 | Rentistas - B v Danubio - B | D | 1-1 |