[9] Guayaquil City 4-2 Olmedo [16] 2021-10-16 20:00
Estadio: Estadio Christian Benitez Betancourt Round: 10
Árbitro: Roddy Zambrano Home Manager: Pool Gavilanez Away Manager: Luis Espinel
Head to Head
| Ecuador - Serie A | 2021/05/04 00:00 | Olmedo v Guayaquil City | D | 0-0 |
| Ecuador - Serie A | 2020/10/15 19:15 | Olmedo v Guayaquil City | W | 1-2 |
| Ecuador - Serie A | 2020/02/16 20:15 | Guayaquil City v Olmedo | W | 4-1 |
| Ecuador - Serie A | 2019/08/10 22:00 | Guayaquil City v Olmedo | W | 3-0 |
| Ecuador - Serie A | 2019/03/16 20:00 | Olmedo v Guayaquil City | D | 1-1 |