| NCAAF | 11/11 17:00 | 1 | Millersville University of Pennsylvania Marauders v Seton Hill Griffins | W | 10-30 | |
| NCAAF | 11/04 18:00 | 1 | Mercyhurst Lakers v Seton Hill Griffins | W | 0-14 | |
| NCAAF | 10/28 16:00 | 1 | Seton Hill Griffins v Edinboro Fighting Scots | W | 38-28 | |
| NCAAF | 10/21 19:00 | 1 | Seton Hill Griffins v Iup Crimson Hawks | W | 35-28 | |
| NCAAF | 10/14 19:30 | 1 | California Vulcans v Seton Hill Griffins | L | 41-14 | |
| NCAAF | 10/07 18:00 | 1 | Clarion Golden Eagles v Seton Hill Griffins | W | 17-24 | |
| NCAAF | 09/30 20:00 | 1 | Seton Hill Griffins v Gannon University Golden Knights | L | 6-23 | |
| NCAAF | 09/23 19:00 | 1 | Seton Hill Griffins v Slippery Rock | L | 14-35 | |
| NCAAF | 09/16 17:05 | 1 | East Stroudsburg Warriors v Seton Hill Griffins | L | 55-21 | |
| NCAAF | 09/09 16:00 | 1 | Seton Hill Griffins v Shippensburg Raiders | W | 28-23 | |
| NCAAF | 08/31 23:00 | 1 | Wheeling Jesuit v Seton Hill Griffins | L | 35-24 | |
| NCAAF | 11/12 17:00 | 1 | Seton Hill Griffins v Millersville University of Pennsylvania Marauders | L | 10-14 | |
| NCAAF | 11/05 18:00 | 1 | Seton Hill Griffins v Mercyhurst Lakers | W | 7-0 | |
| NCAAF | 10/29 16:00 | 1 | Edinboro Fighting Scots v Seton Hill Griffins | W | 14-45 | |
| NCAAF | 10/22 18:00 | 1 | Iup Crimson Hawks v Seton Hill Griffins | L | 44-7 | |
| NCAAF | 10/15 22:00 | 1 | Seton Hill Griffins v California Vulcans | L | 14-21 | |
| NCAAF | 10/08 20:00 | 1 | Seton Hill Griffins v Clarion Golden Eagles | L | 13-40 | |
| NCAAF | 10/01 16:00 | 1 | Gannon University Golden Knights v Seton Hill Griffins | L | 21-10 | |
| NCAAF | 09/24 22:00 | 1 | Slippery Rock v Seton Hill Griffins | L | 30-2 | |
| NCAAF | 09/17 16:00 | 1 | Seton Hill Griffins v East Stroudsburg Warriors | L | 7-22 | |
| NCAAF | 09/10 17:00 | 1 | Shippensburg Raiders v Seton Hill Griffins | L | 36-17 | |
| NCAAF | 09/01 23:00 | 1 | Wheeling Jesuit v Seton Hill Griffins | L | 25-11 | |
| NCAAF | 11/13 18:00 | 1 | Lock Haven v Seton Hill Griffins | W | 7-59 | |
| NCAAF | 11/06 16:00 | 1 | Seton Hill Griffins v Iup Crimson Hawks | L | 3-38 | |
| NCAAF | 10/30 20:00 | 1 | California Vulcans v Seton Hill Griffins | L | 42-14 | |
| NCAAF | 10/23 16:00 | 1 | Clarion Golden Eagles v Seton Hill Griffins | W | 0-49 | |
| NCAAF | 10/16 20:00 | 1 | Seton Hill Griffins v Gannon University Golden Knights | L | 10-14 | |
| NCAAF | 10/09 16:00 | 1 | Mercyhurst Lakers v Seton Hill Griffins | W | 17-19 | |
| NCAAF | 10/02 20:00 | 1 | Seton Hill Griffins v Edinboro Fighting Scots | L | 7-17 | |
| NCAAF | 09/25 22:00 | 1 | Seton Hill Griffins v Slippery Rock | L | 17-41 |