| NCAAF | 11/04 18:00 | 1 | Fayetteville State Broncos v Winston-Salem State | L | 40-34 | |
| NCAAF | 10/28 18:00 | 1 | Johnson C Smith Golden Bulls v Winston-Salem State | L | 35-31 | |
| NCAAF | 10/21 17:30 | 1 | Winston-Salem State v St Augustines Falcons | W | 24-17 | |
| NCAAF | 10/14 17:00 | 1 | Shaw Bears v Winston-Salem State | W | 20-41 | |
| NCAAF | 10/07 17:00 | 1 | Winston-Salem State v Livingstone College Blue Bears | L | 21-23 | |
| NCAAF | 09/30 17:00 | 1 | Lincoln University Lions v Winston-Salem State | L | 30-27 | |
| NCAAF | 09/23 22:00 | 1 | Winston-Salem State v Bluefield State | W | 30-0 | |
| NCAAF | 09/16 22:00 | 1 | Winston-Salem State v Elizabeth City State Vikings | W | 24-7 | |
| NCAAF | 09/09 19:30 | 1 | Ohio Dominican Panthers v Winston-Salem State | L | 26-14 | |
| NCAAF | 09/02 20:00 | 1 | North Carolina Central Eagles v Winston-Salem State | L | 47-21 | |
| NCAAF | 11/05 20:00 | 1 | Winston-Salem State v Fayetteville State Broncos | L | 6-14 | |
| NCAAF | 10/29 17:00 | 1 | Winston-Salem State v Johnson C Smith Golden Bulls | W | 28-7 | |
| NCAAF | 10/22 17:00 | 1 | St Augustines Falcons v Winston-Salem State | W | 14-41 | |
| NCAAF | 10/15 17:30 | 1 | Winston-Salem State v Shaw Bears | W | 17-10 | |
| NCAAF | 10/08 17:00 | 1 | Livingstone College Blue Bears v Winston-Salem State | L | 20-17 | |
| NCAAF | 10/01 17:30 | 1 | Winston-Salem State v Lincoln University Lions | - | Cancelled | |
| NCAAF | 09/24 22:00 | 1 | Chowan University Hawks v Winston-Salem State | L | 21-7 | |
| NCAAF | 09/17 16:00 | 1 | Elizabeth City State Vikings v Winston-Salem State | L | 20-17 | |
| NCAAF | 09/10 22:00 | 1 | North Carolina Central Eagles v Winston-Salem State | L | 41-0 | |
| NCAAF | 09/04 20:00 | 1 | Winston-Salem State v Central State | L | 21-41 | |
| NCAAF | 11/06 18:00 | 1 | Fayetteville State Broncos v Winston-Salem State | L | 10-3 | |
| NCAAF | 10/30 17:00 | 1 | Shaw Bears v Winston-Salem State | L | 38-14 | |
| NCAAF | 10/23 17:00 | 1 | Winston-Salem State v Livingstone College Blue Bears | W | 21-0 | |
| NCAAF | 10/16 17:30 | 1 | Winston-Salem State v St Augustines Falcons | W | 41-0 | |
| NCAAF | 10/09 17:00 | 1 | Johnson C Smith Golden Bulls v Winston-Salem State | W | 12-26 | |
| NCAAF | 10/02 22:00 | 1 | Chowan University Hawks v Winston-Salem State | L | 73-7 | |
| NCAAF | 09/25 17:30 | 1 | Winston-Salem State v Elizabeth City State Vikings | L | 14-19 | |
| NCAAF | 09/18 22:00 | 1 | North Carolina Central Eagles v Winston-Salem State | L | 20-13 | |
| NCAAF | 09/11 23:00 | 1 | Catawba Indians v Winston-Salem State | L | 28-6 | |
| NCAAF | 11/09 18:30 | 1 | Winston-Salem State v Fayetteville State Broncos | L | 17-31 |