Estadio: Dana J. Dykhouse Stadium Round: 1
Home Manager: Jimmy Rogers Away Manager: Mark Farley
| NCAAF | 2022/11/05 21:00 | South Dakota State v Northern Iowa Panthers | L | 31-28 |
| NCAAF | 2021/10/23 19:00 | Northern Iowa Panthers v South Dakota State | W | 26-17 |
| NCAAF | 2021/02/20 01:00 | South Dakota State v Northern Iowa Panthers | L | 24-20 |
| NCAAF | 2019/12/07 19:00 | Northern Iowa Panthers v South Dakota State | W | 13-10 |
| NCAAF | 2019/11/16 20:00 | Northern Iowa Panthers v South Dakota State | L | 7-38 |
| NCAAF | 2018/10/20 21:00 | Northern Iowa Panthers v South Dakota State | W | 24-9 |
| NCAAF | 2017/12/02 20:00 | Northern Iowa Panthers v South Dakota State | L | 22-37 |
| NCAAF | 2017/10/14 19:00 | South Dakota State v Northern Iowa Panthers | W | 18-38 |
| NCAAF | 2023/10/07 23:00 | Northern Iowa Panthers v Indiana State | W | 27-20 |
| NCAAF | 2023/09/30 18:00 | Youngstown State v Northern Iowa Panthers | W | 41-44 |
| NCAAF | 2023/09/16 22:00 | Northern Iowa Panthers v Idaho State | W | 41-17 |
| NCAAF | 2023/09/09 21:00 | Weber State v Northern Iowa Panthers | L | 34-17 |
| NCAAF | 2023/09/02 18:00 | Northern Iowa Panthers v Iowa State | L | 9-30 |
| NCAAF | 2022/11/19 19:00 | Northern Iowa Panthers v South Dakota | W | 58-14 |
| NCAAF | 2022/11/05 21:00 | South Dakota State v Northern Iowa Panthers | L | 31-28 |
| NCAAF | 2022/10/29 19:00 | Northern Iowa Panthers v SO Illinois | W | 37-36 |
| NCAAF | 2023/10/07 23:00 | South Dakota State v Illinois State | W | 40-21 |
| NCAAF | 2023/09/30 19:00 | North Dakota v South Dakota State | W | 21-42 |
| NCAAF | 2023/09/16 19:30 | Drake Bulldogs v South Dakota State | W | 7-70 |
| NCAAF | 2023/09/09 23:00 | Montana State v South Dakota State | W | 16-20 |
| NCAAF | 2023/09/01 00:00 | South Dakota State v Western Oregon | W | 45-7 |
| NCAAF | 2023/01/08 19:00 | North Dakota State v South Dakota State | W | 21-45 |
| NCAAF | 2022/12/17 21:00 | Montana State v South Dakota State | W | 18-39 |
| NCAAF | 2022/12/10 17:00 | Holy Cross v South Dakota State | W | 21-42 |