Estadio: Dana J. Dykhouse Stadium Round: 1
Home Manager: Jimmy Rogers Away Manager: Mark Farley
| NCAAF | 2022/11/05 21:00 | South Dakota State v Northern Iowa Panthers | L | 31-28 |
| NCAAF | 2021/10/23 19:00 | Northern Iowa Panthers v South Dakota State | W | 26-17 |
| NCAAF | 2021/02/20 01:00 | South Dakota State v Northern Iowa Panthers | L | 24-20 |
| NCAAF | 2019/12/07 19:00 | Northern Iowa Panthers v South Dakota State | W | 13-10 |
| NCAAF | 2019/11/16 20:00 | Northern Iowa Panthers v South Dakota State | L | 7-38 |
| NCAAF | 2018/10/20 21:00 | Northern Iowa Panthers v South Dakota State | W | 24-9 |
| NCAAF | 2017/12/02 20:00 | Northern Iowa Panthers v South Dakota State | L | 22-37 |
| NCAAF | 2017/10/14 19:00 | South Dakota State v Northern Iowa Panthers | W | 18-38 |